Hearing is a critical part of our lives, connecting us to the world around us. But did you know that certain medications can damage your hearing? These medications are referred to as ototoxic drugs, and their side effects can range from temporary ringing in the ears to permanent hearing loss.
In this blog, we’ll dive deep into what ototoxicity is, which medications are considered ototoxic, and how you can protect your hearing health.

What Is Ototoxicity?
Ototoxicity refers to damage to the inner ear (cochlea or vestibular system) caused by exposure to certain drugs or chemicals. This damage can lead to hearing loss, tinnitus (ringing in the ears), or even balance problems. In many cases, the effects are reversible once the medication is stopped, but some drugs can cause permanent damage.
Common Ototoxic Medications
Many medications, both prescription and over-the-counter, have ototoxic effects. Here’s a breakdown of the most common culprits:
1. Antibiotics
Aminoglycosides (e.g., gentamicin, streptomycin): These are powerful antibiotics used to treat severe infections. However, they are known to cause hearing loss, especially with prolonged use.
Other antibiotics like vancomycin and erythromycin have also been linked to hearing damage in certain cases.
2. Chemotherapy Drugs
Cisplatin: Widely used in cancer treatment, cisplatin is highly ototoxic and can lead to permanent hearing loss.
Carboplatin, another chemotherapy drug, is also associated with hearing damage.
3. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Medications like aspirin, ibuprofen, and naproxen can cause temporary tinnitus or hearing loss, particularly at high doses.
4. Loop Diuretics
Drugs like furosemide (Lasix) and bumetanide, often prescribed for heart failure or kidney conditions, can lead to temporary hearing issues.
5. Quinine
Used for malaria treatment, quinine has been associated with tinnitus and temporary hearing loss.

Signs of Ototoxicity
If you are taking ototoxic medications, watch for these warning signs:
Persistent ringing in the ears (tinnitus)
Difficulty understanding speech, especially in noisy environments
Feeling of fullness in the ears
Loss of balance or dizziness
Gradual or sudden hearing loss
If you notice these symptoms, consult your healthcare provider or an audiologist immediately.
How Ototoxic Drugs Cause Hearing Damage
These medications can damage the hair cells in the cochlea, which are essential for converting sound waves into electrical signals sent to the brain. Once these hair cells are damaged, they don’t regenerate, leading to potential permanent hearing loss.
How to Protect Your Hearing
1. Discuss Your Medications: If you’re prescribed an ototoxic drug, ask your doctor about potential alternatives or ways to minimise the risk.
2. Regular Hearing Tests: If you’re on long-term ototoxic medication, schedule regular hearing tests to monitor your auditory health.
3. Use the Lowest Effective Dose: Avoid high doses of medications like aspirin or ibuprofen unless absolutely necessary.
4. Avoid Noise Exposure: Loud environments can worsen hearing damage caused by ototoxic drugs.
5. Stay Hydrated: Proper hydration can reduce the risk of drug-induced ear damage.
Are There Alternatives to Ototoxic Drugs?
In some cases, non-ototoxic alternatives may be available. For example, some antibiotics or diuretics have less potential for hearing damage. Always consult with your healthcare provider before making any changes to your medications.
Ototoxic drugs play a vital role in treating serious health conditions, but their potential to cause hearing loss is a significant concern. By staying informed, discussing risks with your doctor, and monitoring your hearing health, you can reduce the likelihood of permanent damage.
If you’re experiencing hearing loss or tinnitus, schedule a hearing test with our certified audiologist today. Early intervention is key to preserving your hearing health.

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